Dados do Trabalho

Título

CANCER DE MAMA EM MULHERES: CARACTERIZAÇAO DOS CASOS INCLUIDOS NOS REGISTROS HOSPITALARES DE CANCER DO ESTADO DE SAO PAULO E FATORES ASSOCIADOS AOS ESTADIOS AVANÇADOS

Título em Inglês

BREAST CANCER IN WOMEN: CHARACTERIZATION OF CASES INCLUDED IN THE HOSPITAL-BASED CANCER REGISTRY OF THE STATE OF SÃO PAULO AND FACTORS ASSOCIATED WITH ADVANCED STAGES

Introdução

Breast cancer is a public health problem worldwide, being the most common malignancy in the female population. It is a potentially curable disease if diagnosed early. The advanced stage at the time of diagnosis is associated with increased morbidity and low survival for these women.

Objetivos

To describe the sociodemographic, clinical and anatomopathological characteristics of breast cancer cases in women included in the hospital-based cancer registry (RHC) of the Fundação Oncocentro de São Paulo (FOSP, in Portuguese), and to investigate factors associated with the clinical stage at diagnosis.

Métodos

The study design was a case series. The sample consisted of women with breast cancer diagnosed between 2000 and 2014 and included in the RHC-FOSP. The outcome variable was a clinical-stage (stage 0-II versus III-IV). The explanatory variables were age at diagnosis and educational level. This study was approved by the Human Research Ethics Committee of the Botucatu Medical School, São Paulo State University, Brazil.

Resultados

The study included 84,987 women with in situ and invasive breast cancer diagnosed between 2000-2014. The average age of women at diagnosis was 56.7 years (95%CI 56.6 - 56.8 years). Sixty-five percent of cases completed elementary school or less and the most frequent histological type was ductal carcinoma (77.2%). During the study period, there was a slight decrease in the proportion of tumors in more advanced stages, from 39.8% in 2000 to 32.6% in 2014. There was a statistically significant association between age at diagnosis and educational level with the women's grouped clinical stage. Women of older age and those with a higher education level had reduced odds ratios of having tumors in more advanced stages at the time of diagnosis.

Conclusões

These findings may contribute to the development of policies for the identification of breast tumors at earlier stages.

Palavras Chave

Breast Neoplasms, Delayed Diagnosis, Prognosis. 

Área

EPIDEMIOLOGY, RISK, AND PREVENTION - Epidemiology