Dados do Trabalho

Título

SOBREVIDA MEDIA DAS PACIENTES TRATADAS POR CANCER DE MAMA ESTADIO I E CLINICAMENTE N0, NO PERIODO DE JANEIRO DE 2010 A DEZEMBRO DE 2019 SUBMETIDAS A LINFONODECTOMIA AXILAR OU LINFONODO SENTINELA.

Título em Inglês

AVERAGE SURVIVAL OF PATIENTS TREATED BY STAGE I AND CLINICALLY N0 BREAST CANCER, IN THE PERIOD FROM JANUARY 2010 TO DECEMBER 2019 SUBMITTED TO AXILLARY LYMPHONODECTOMY OR SENTINEL LYMPH NODE

Introdução

Axillary lymph node involvement is a important asset in breast cancer staging, prognosis and predicts therapeutic specificity. Despite the large proportion of advanced cases in the Public Health System in Brazil, about 67% of our patients are in stages I and II. The absence of reports of survival in Brazil motivated us to carry out this study.

Objetivos

To retrospectively assess the median survival of 2170 stage I breast cancer patients who underwent axillary lymph nodes dissection (ALND) compared to those who underwent only sentinel lymph node biopsy (SLNB) using the patent blue technique

Métodos

This is a cross-sectional, retrospective clinical study, aiming to assess the average survival of patients with stage I breast cancer without clinical lymph node involvement (N0), submitted to ALND after positive SLNB during the surgical procedure or SLNB failure guided by patent blue. 2170 patients were included in stage I. The study was carried out between January 2010 and December 2019.

Resultados

The average number of sentinel lymph nodes was 3.2 lymph nodes. In patients in stage I, the mean survival in more than 5 years was higher in those submitted only to a 98.31% SLNB (N = 1228), than in those who performed ALND, survival was 94.13% (N = 867). In less than 5 years, longer survival was observed in patients who underwent ALND 5.87% (N = 54). Axillary lymph node dissection was essential in the treatment of breast cancer for many years in the last. However, the high morbidity directly interfered with the patient's quality of life. Therefore, long-term studies introduced SLNB as a standard for axillary evaluation in clinically T1, T2 and N0 patients, noting that patients with negative SLNB and not submitted to ALND, showed no difference in axillary recurrence, disease-free survival and overall survival. Our results at Stage I, although the 5-year period is short, overlap with those in the literature. Over the years, surgical axillary staging and management of early breast cancer have evolved, becoming less invasive and more conservative, with imaging exams playing an important role in axillary disease, with the use of improved techniques in an attempt to minimize intervention.

Conclusões

In view of the data presented, it can be concluded that the average survival in more than 5 years was higher in patients who underwent only 98.31% SLNB compared to those who underwent ALND (94.13%).

Palavras Chave

SURVIVAL;AXILLARY LYMPHONODECTOMY;SENTINEL LYMPH NODE

Área

DETECTION / DIAGNOSIS - Axillary Nodes